The latest edition of our newsletter can be read at the link below: NC-IUPHAR_Newsletter_Summer_2014 Special features covered in this issue include: A detailed profile of the PubChem database contributed by their lead scientist Evan Bolton, with whom we have worked…
Blog Archives
WCP2014: Abstracts from NC-IUPHAR members
The 17th World Congress of Basic and Clinical Pharmacology (WCP2014) is now rapidly approaching and several NC-IUPHAR members will be attending the Congress. The followings talks will be presented on Tuesday 15th July 2014 15.30-17.00 in Track 6 of the…
Posted in Events
Case studies in chemical curation III: complexes and component mixtures
The issue of specified mixtures that include pharmacologically active chemical structures is complex and curatorially challenging, as described by this presentation on the topic. This post will briefly cover our handing of salts. A substance in an approved drug preparation may…
Posted in Chemical curation
Guide to PHARMACOLOGY out and about: Spring 2014 conferences and meetings
In April one of our curators, Helen Benson, represented the team at the Seventh International Biocuration Conference at the University of Toronto, and presented a poster outlining our approved drug and clinical target curation. This visit followed the previous year’s…
Posted in Events
New features on the Guide to PHARMACOLOGY: June 2014
Our latest database update took place on Monday 16th June and this post summarises the new content and features on the site. Website demo Our ‘Help’ pages now include a ‘walkthrough’ demo of the website produced by Prof. Tony Harmar…
Posted in Database updates
Case study in chemical curation II: Racemates and how to represent them
Where the drug is a racemate, should we go ‘flat’? Example: ketoconazole Many drugs are racemates, as indicated by their INN document or FDA label. This presents us with a curatorial decision: should we represent both of the enantiomers as…
Posted in Chemical curation
BPS awards JR Vane Medal to Professor Tony Harmar
The British Pharmacological Society today announced the winners of several of their 2014 awards and prizes. Among these awards is the JR Vane Medal which has been awarded posthumously to Professor Tony Harmar. This award reflects the tremendous contribution Tony…
Posted in Uncategorized
Will the real drugs please stand up? Case studies in chemical curation I
Our database now contains over 6500 ligands, spanning 7 chemical classes. An important part of our curation work is to ensure the chemical structures of these ligands are accurate through both careful curation of new ligands and the running of…
Posted in Chemical curation
New content and features on The Guide to PHARMACOLOGY: our April 2014 update
Last month we updated our site to include the results of our curation efforts since the start of the year. Our main focus of 2014 so far has been curation of approved drugs and clinical targets, and the site has…
Tagged with: Alzheimer‘s disease, Approved drugs, clinical targets
Posted in Database updates, Drug targets
Posted in Database updates, Drug targets
WCP 2014: 17th World Congress of Basic and Clinical Pharmacology in Cape Town
We recommend that all our users consider attending WCP2014 (early bird registration has now been extended until March 31st). Members of the IUPHAR/BPS Guide to PHARMACOLOGY database team, and NC-IUPHAR committee members will be attending and look forward to…
Posted in Events
Chemical search drawing tools: updating Java and security exceptions
Regular users of the Guide to PHARMACOLOGY will be aware that the site includes a ‘Chemical structure search’ function whereby users can draw chemical structures or parts of structures and use these to search against the database. Users can also…
Posted in Technical
Drug and target lists on the Guide to PHARMACOLOGY
Given the intense interest in drugs and their human targets, both in pharmacology and chemical biology, obtaining a simple list of either is surprisingly difficult. There are many reasons for this. One of them is that those lists that can…
