Blog Archives

Database Release 2020.4

The latest release of the Guide to PHARMACOLOGY database, version 2020.4, has now been made. Coronavirus The Guide to Pharmacology coronavirus information page continues to be updated on a regular basis to capture the latest pharmacological strategies under investigation to mitigate against

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Posted in Database updates

GtoPdb pre-release ligands (2020.4)

These are some of the ligands under curation (pre-release) in the Guide to Pharmacology. We expect them to be available on the website at the next database release (2020.4). Ligand ID: 11132 Name: otilimabComment: Otilimab (MOR103, GSK3196165) is a clinical

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Posted in Database updates

Database Release 2020.3

The latest release of the Guide to PHARMACOLOGY database, version 2020.3, has now been made. A large focus of our curation over the last couple of month since our 2020.2 release We are pleased to have been able to make

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Posted in Database updates, Technical

GtoPdb pre-release ligands (2020.3)

These are some of the ligands under curation (pre-release) in the Guide to Pharmacology. We expect them to be available on the website at the next database release (2020.3). Ligand ID: 10891 Name: aviptadil Comment: Aviptadil is a vasoactive intestinal

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Posted in Database updates

Database Release 2020.2

We are pleased to have been able to make an expeditious database release (version 2020.2), following on from our last update in March 2020 in order to make public new curation specifically related to SARS-CoV-2. Content Updates GtoPdb now includes

Posted in Database updates, Technical

GtoPdb pre-release ligands (2020.2)

These are some of the ligands under curation (pre-release) in the Guide to Pharmacology. We expect them to be available on the website at the next database release (2020.2 – no earlier than April 2020).  Ligand ID: 10716 Name: PRD_002214

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Posted in Database updates

Database Release 2020.1

We are pleased to announce our first database release of 2020 – version 2020.1. Coronavirus (Covid-19) We have added a new coronavirus page to the Guide to Pharmacology which aims to consolidate key pharmacological information and resources related to coronavirus.

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Posted in Database updates, Technical

Database Release 2019.5

Our fifth and final database release of 2019 has been made and includes a number of minor content and website updates. Crucially, it comes at a time when we have just published our most recent database update in Nucleic Acids

Posted in Database updates, Technical

Database Release 2019.4

We are very pleased to announce our a new release of the IUPHAR/BPS Guide to Pharmacology. This version (2019.4) is the fourth this year and includes the first full-release of the IUPHAR/MMV Guide to Malaria Pharmacology. Content Updates GtoPdb now

Posted in Database updates, Guide to Immunopharmacology, Guide to Malaria Pharmacology, Technical

Database Release 2019.3

We have now made the third IUPHAR/BPS Guide to Pharmacology database release of 2019 (2019.3). It includes updates focussed on preparation for the next edition of The Concise Guide to PHARMACOLOGY (2019/20), due out later this year. Content Updates GtoPdb

Posted in Database updates, Guide to Malaria Pharmacology, Hot Topics, Technical

Database Release 2019.2

We are pleased to announce a new IUPHAR/BPS Guide to Pharmacology database release! This release, 2019.2, is the second of the year and includes updates focussed on preparation for the next edition of The Concise Guide to PHARMACOLOGY (2019/20), due

Posted in Database updates

Database Release 2019.1

Our first database release of 2019 (2019.1) is now available. This update contains the following new features and content changes: Content Updates GtoPdb contains over 9,400 ligands, with around 7,200 have quantitative interaction data to biological targets. Just over 1,400

Posted in Database updates, Guide to Immunopharmacology, Guide to Malaria Pharmacology

Database release 2018.4

Our fourth database release of the year, 2018.4, is now available (n.b. the PubChem update statistics and link sets will be posted in a couple of weeks).   This update contains the following new features and content changes: Content Updates GPCRs:

Posted in Database updates, Guide to Immunopharmacology, Guide to Malaria Pharmacology

Database release 2018.3

Our third database release of the year, 2018.3, is now available. This update contains the following new features and content changes: Content updates GPCRs: Adenosine receptors Chemokine receptors Cholecystokinin receptors Dopamine receptors Ghrelin receptors Opioid receptors GPR55 receptors NHRs: MRetinoic

Posted in Database updates, Guide to Immunopharmacology, Guide to Malaria Pharmacology

GtoPdb: Database Status Reports

As some of our contacts may know, we hold hemi-annual meetings between IUPHAR, BPS the GtoPdb team, together with invited guests from our collaborators and NC-IUPHAR committee representatives. Covering ~ 2.5 days these usually take place in Paris or Edinburgh.

Posted in Database updates, Technical, Uncategorized

Database release 2018.2

Our second database release of the year, 2018.2, is now available. This update contains the following new features and content changes: Content updates GPCRs: 5-Hydroxytryptamine receptors Adenosine receptors Adrenoceptors Histamine receptors Opioid receptors Lysophospholipid (S1P) receptors Prostanoid receptors NHRs: Mineralocorticoid

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Posted in Database updates, Guide to Malaria Pharmacology

Database release 2018.1

Pharmacology Search results table

The first GtoPdb and GtoImmuPdb beta release of  2018 includes plenty of target and ligand updates as well as announcing some important new features. As always, full content statistics for release 2018.1 can be found on the database about page.

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Posted in Database updates, Technical

Database release 2017.6

The sixth and final IUPHAR/BPS Guide to PHARMACOLOGY release of 2017 has been published on 29th November. This release includes new content for the Guide to IMMUNOPHARMACOLOGY, which is currently still in beta phase. This release includes the following updates

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Posted in Database updates, Guide to Immunopharmacology, Technical

New source cross-references in release 2017.5

(minor updates 15 Sep 2017) The statistics of content are presented as usual in the release notes and The Guide to IMMUNOPHARMACOLOGY has a separate update.  This post describes changes and updates to other resources we provide links to, that

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Posted in Database updates, Technical

Database release 2017.5

The 5th IUPHAR/BPS Guide to PHARMACOLOGY database release of 2017 includes updates to several target families, and new targets and ligands added, focusing on those relevant to immunopharmacology. We also announce a new organisation for ligand families and groups. This

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Database release 2017.4

Our 4th database release of 2017 was published on 23rd May 2017. It now includes 15133 interactions between 2813 targets and 8900 ligands. For full release statistics see the Guide to PHARMACOLOGY About page. Target Updates Updates have been made to

Posted in Database updates, Guide to Immunopharmacology, Technical

Database release 2017.2

Our 2nd database release of 2017 was published on 23rd March 2017. It now includes 15019 interactions between 2809 targets and 8832 ligands. For full release statistics see the About the Guide to PHARMACOLOGY page. Target updates The major part

Posted in Concise Guide to Pharmacology, Database updates, Technical

Database release 2017.1

We are pleased to announce our first database release of 2017 on 26th Jan 2017. While there are no major updates in this release, it includes several bug fixes and new ligands of relevance to immunopharmacology. Our new portal, the

Posted in Database updates, Technical

GtoPdb database release 2016.4

We are pleased to announce our fourth database release of 2016. Version 2016.4 was published on 13th October 2016. The database is available through the Guide to Pharmacology website, download pages and web-services.

Posted in Database updates

GtoPdb database release 2016.3

We are pleased to announce our third database release of 2016. Version 2016.3 was published on 21st July 2016. The database is available through the Guide to Pharmacology website, download pages and web-services. In this release, our curators have added comments to all approved

Posted in Database updates

GtoPdb database release 2016.2

The latest update of the database, version 2016.2, has been released (30th March 2016). The summary of the main updates is below. Database content in various formats can be downloaded from our download pages and accessed via web services. This

Posted in Database updates

GtoPdb database release 2016.1

Database release 2016.1, now features 14249 curated interactions.

Posted in Database updates

GtoPdb database release 2015.3

Our total number of curated interactions now stands at 13859. New BLAST tool for sequence-based searching of targets available at http://www.guidetopharmacology.org/blast/.

Posted in Database updates

Database Release August 2015

The first version of our REST web services is now available for beta testing

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Posted in Database updates, Technical

Database Update March 2015

The first release of 2015 includes major updates in several areas. More than 420 new ligands were added.

Posted in Database updates

New content and features: November 2014 update

The latest database version (2014.3) was released on 5th November and includes many content updates and new website enhancements. The current release now covers 7220 distinct ligands interacting at 2708 protein targets (see full statistics on our About page). This

Posted in Database updates

New features on the Guide to PHARMACOLOGY: June 2014

Our latest database update took place on Monday 16th June and this post summarises the new content and features on the site. Website demo Our ‘Help’ pages now include a ‘walkthrough’ demo of the website produced by Prof. Tony Harmar

Posted in Database updates

New content and features on The Guide to PHARMACOLOGY: our April 2014 update

Last month we updated our site to include the results of our curation efforts since the start of the year. Our main focus of 2014 so far has been curation of approved drugs and clinical targets, and the site has

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Posted in Database updates, Drug targets