A system of rigorous clinical trials and regulation exist to ensure that a new drug is safe and effective when reaching the market. However, natural human genetic variation(s) may cause individuals to respond differently to the same medication. A collaboration…
Blog Archives
Proteases in the latest GtoPdb release
The team have surfaced more fruits of our labour in release 2014.3 of GtoPdb (this is now our official acronym for the database). This post will highlight protease expansion during this curation cycle (see page 10 in our newsletter for an introduction to our…
Posted in Drug targets
A Pharmacologists’ Guide to Resolving Chemical Structures and their Protein Targets from the Literature
This is an introduction to resolving bioactive ligands and their protein targets from the literature. It includes their conversion to standardised molecular identifiers so these can be communicated to the Guide to PHARMACOLOGY (GtoPdb) team. (n.b. identifying what is already…
New content and features on The Guide to PHARMACOLOGY: our April 2014 update
Last month we updated our site to include the results of our curation efforts since the start of the year. Our main focus of 2014 so far has been curation of approved drugs and clinical targets, and the site has…
Tagged with: Alzheimer‘s disease, Approved drugs, clinical targets
Posted in Database updates, Drug targets
Posted in Database updates, Drug targets
Drug and target lists on the Guide to PHARMACOLOGY
Given the intense interest in drugs and their human targets, both in pharmacology and chemical biology, obtaining a simple list of either is surprisingly difficult. There are many reasons for this. One of them is that those lists that can…
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