Blog Archives

Anti-infective pilot entries

GtoPdb has been traditionally focused on the pharmacology associated with human diseases (i.e. we have not been funded to cover anti-infectives).  In 2017 we have been exploring possible funding opportunities to extend into  expert curation of anti-infectives, particularly in the

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Reference Citations in BJP and NAR metrics

Introduction Like other database resources, we collate measures of impact for various uses. These include our own internal bi-annual IUPHAR/GtoPdb review meetings, documenting outputs of past grants and applications for new ones. While there is a widening choice of these

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GtoPdb Ligands in PubChem

GtoPdb and  its precursor IUPHAR-DB have been capturing the structures of pharmacologically relevant ligands since 2005.  The fig.1. snapshot below  shows the approved drug section of our eight-category ligand classification As an active collaboration with the  PubChem team, we have

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Why Data Citation Is a Computational Problem

By Peter Buneman The database development team encouraged me to write this off-topic blog on data citation, as it may be of interest to people involved with the IUPHAR/BPS Guide to Pharmacology (GtoPdb). It must be almost ten years ago

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SynPharm: A New Annexe to the Guide to PHARMACOLOGY

We have created a new sister database to the main Guide to PHARMACOLOGY (GtoPdb) – SynPharm, a database of drug-responsive protein sequences. Each sequence in SynPharm is derived from a GtoPdb interaction. In each case we have identified the continuous

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Recent DrugBank Changes

The DrugBank database has just announced (09 May 2016) more restrictive access conditions including user registration. Not unexpectedly, this has prompted discussion on Twitter and elsewhere (e.g. ThinkLab. including some from the DrugBank team).  We enjoy long-standing contacts with the

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Assessment of GtoPdb in-links

A valuable aspect of biological databases in general and the IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) in particular, are out-links to and in-links from, other relevant resources.

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