The IUPHAR/BPS Guide to Pharmacology has made changes to how the database and REST API (Web Services) are accessed.
As from 18th August 2026 users are required to register with the Guide to Pharmacology in order to log in to use the website.
Additionally registered users will need to request an API Key in order to access our REST API. The change to require an API Key will be implemented around 15th-17th September 2026, until then access to the REST API without the need to an API Key will remain in place.
Why are we making these changes?
These changes are necessary so that we can collect accurate user access data to help us maintain GtoPdb as an open-access, freely available resource. There will be no cost for users from non-commercial organisations.
Commercial organisations that use GtoPdb already pay access-fees which support the maintenance, curation and sustainability of the resource. Commercial users should read our sustainability statement for more information on commercial access fees.
As we roll out these changes there will be a guest login feature available, which will allow users access to the website without registering (but without providing access to the REST API). The guest login will remain in place until 15th-17th September 2026 as we establish the new registration system, after which all users need to be register.
If you have any questions about these changes or accessing GtoPdb, please get in touch with us.
guidetopharmacology blog 
I tried to register but was frustrated by the demand for a User Name after I had filled in the reg form which did NOT ask me for a User name. What IS a User name? And where do I define it?
Also it would be good to provide an email address when (during registration) it says “please contact us if you have trouble registering”
Hello, I’m sorry you have been frustrated by the registration process. The new system is only just being brought online. I can see you have tried to register, but will have be redirected to a page that required a login.
This is an error.
The URL in the verification email was incorrect. I will send you a new verification email, which should hopefully work and not redirect you to the wrong page.
Apologies for the inconvenience,
Simon
you can contact us directly at enquiries@guidetopharmacology.org
(clicking the contact us link hyperlink should have given a pop-up to reveal the email).