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Hot Topics: Endothelin-1 pathway, a new therapeutic target for COVID-19

SARS-CoV-2 gains entry into the body mainly via the lungs. After entering the blood, the virus rapidly multiplies to infect nearby cells. Endothelial cells line every blood vessel and have a surface area similar to a tennis court. These cells

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Hot Topics: SARS-CoV-2 and the truncated ACE-2 variant

ACE2 (Guide to Pharmacology Target id: 1614) normally functions as an enzyme metabolising peptides that regulate the cardiovascular system. As is well known though, it has recently gained additional scientific fame by also acting as a receptor for SARS-CoV-2. This study [1] compared

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