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Hot Topics: FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2 This manuscript (1) reports on extensive and compelling experimental evidence and translational data from retrospective review of clinical registries, which show that pharmacological inhibition of the farnesoid X receptor (FXR)

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Hot Topics: A new study shows that human ageing is absolutely precise, when disease is eliminated, and accompanied by a disintegration of metabolic efficiency

Human ageing is just disintegration, but absolutely precise, linked to loss of VO2 max, which is why COVID is age-related. A new study (1) shows that the decline in human performance with age at 5000 m, an athletic event requiring

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