At the beginning of October 2018 we held a meeting in Edinburgh focussed on the launch of the IUPHAR Guide to IMMUNOPHARMACOLOGY. Invited speakers contributed to productive discussions on the varying challenges and opportunities in immunopharmacology research.
Immunopharmacology: The New Frontier
There has been immense progress in immunopharmacology, but there are insufficient links between the immunological and pharmacological sciences. Thus, we have set up several initiatives.
IUPHAR set up an immunopharmacology section (Immuphar) chaired by Francesca Levi-Schaffer.
IUPHAR has signed an agreement with International Union of Immunological Sciences (IUIS, President Alberto Mantovani, who has also made major contributions to the field of check-point inhibitors) to ensure collaboration and cooperation.
IUPHAR, NC-IUPHAR (chair Steve Alexander), the University of Edinburgh (PI, Pr Jamie Davies) and the Edinburgh database group (IUPHAR/BPS Guide to Pharmacology; www.guidetopharmacology.org) have been able to set up a new database on the drug targets in immunopharmacology, financed by a major grant from the Wellcome Trust. This is www.guidetoimmunopharmacology.org, which has been recently launched and is freely available to all. The BPS finance two staff in the Edinburgh group for which IUPHAR is immensely grateful.
To celebrate this launch, a focussed immunopharmacology meeting was organised, which included the Anthony Harmar memorial lecture. This report provides a a summary of the meeting presentations, discussions and outcomes.
The launch of GtoImmuPdb has also been reported in a Nature Review Immunology Web Watch article: Harding SD et al. (2018). A new guide to immunopharmacology. Nat Rev Immunol, 18(12):729. [PMID:30327546]
Please read our detail meeting report which summarises the presentations, discussions and outcomes. Download the Meeting Report (PDF)
Access slidesets from the presentations below (or on our website):
|Anthony Harmer Memorial Lecture: Decision-making in lung immunity||Prof. Tracy Hussell||Download slides: pptx | pdf|
|The Guide to IMMUNOPHARMACOLOGY||Dr. Elena Faccenda, Dr. Chris Southan and Dr. Simon Harding||Download slides: pptx | pdf|
|Macrophage plasticity in immunopathology and cancer: from bench to bedside||Prof. Alberto Mantovani||Download slides: pptx | pdf|
|Targeting Pattern Recognition Receptor signalling for therapeutic approaches||Prof. Clare Bryant||slides not available|
|Discovering the right target in inflammatory disease||Prof. Iain McInnes||slides not available|
|Is Atherosclerosis a Systemic or a Vascular Immune Disease?||Prof. Pasquale Maffia||slides not available|
|Inhibit Activation or Activate Inhibition of Mast Cells and Eosinophils: Which Weapon is Better to Fight Allergic Diseases?||Prof. Francesca Levi-Schaffer||Download slides: pptx | pdf|
|IUPHAR: natural products and immunology||Prof. Michael Spedding||Download slides: pptx | pdf|
|Human type I interferon up regulation – worth targeting?||Prof. Yanick Crow||Download slides: pptx | pdf|
|A review on kinase targets in immunological indications||Dr. Dorian Fabbro||Download slides: pdf|