Our third database release of the year, 2018.3, is now available. This update contains the following new features and content changes:
MRetinoic acid receptor
Natriuretic peptide receptor family
The existing Antimalarial targets family has been updated with 5 new P. falciparum (3D7) targets:
- PfATP4 (Plasmodium falciparum ATPase4)
- PfDHFR-TS (Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase)
- PfDXR (Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase)
- PfeEF2 (Plasmodium falciparum elongation factor 2)
- PfPI4K (Plasmodium falciparum phosphatidylinositol 4-kinase)
A new Antimalarial ligands family has been created and contains 30 ligands all tagged as an antimalarial in the database. Of these 30, 20 are new ligands curated for this release.
New website features
GtoImmuPdb now public
The IUPHAR Guide to IMMUNOPHARMACOLOGY is now at its first public release and is no longer considered a beta version. We will continue to develop the portal and specific immuno interfaces as well as continuing curation towards its official launch in October 2018. This will be at the BPS Immunopharmacology: Challenges, opportunities and research tools meeting in Edinburgh, 1st-2nd October 2018.
Disease Summary Pages
The disease summary pages have been modified to improve the payout of target information and provide links to help to understand terms and symbols. The display of associated ligand is now in a sortable table and the comments section includes bioactivity comments where present. We have also include links to the specific clinical data or bio-activity tabs on ligand summary pages.