GtoPdb database release 2016.1

We are pleased to announce the first database release of 2016, version 2016.1 published on 4th February 2016. Below is a summary of the main updates. As always, database content, of various types and formats can be downloaded from our download pages.

Here is a summary of the latest updates:

Target updates:

• GPCR updates:
  • Adenosine receptors
  • Histamine receptors
  • Lysophospholipid (LPA) receptors
  • Lysophospholipid (S1P) receptors
  • Melanocortin receptors
  • Melatonin receptors
  • Prolactin-releasing peptide receptor
• NHR updates:
  • Estrogen Receptors
  • Estrogen-related receptors
  • Peroxisome proliferator-activated receptors
  • Rev-Erb receptors
  • Retinoic acid receptors
  • Retinoid X receptors
• Enzyme updates:
  • Nitric Oxide synthases
• Ion-Channel updates:
  • Ryanodine receptor has been re-classified as a voltage-gated ion channel (previously it was a ligand-gated ion channel)

Database Statistics

In total the database now contain 14,249 curated interactions across 2,769 target and 8,328 ligands.

Breakdown of GtoPdb content by human target class

Breakdown of GtoPdb content by ligand class

View all the latest database content stats here.